Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135220 | 0.84 | HTR2C (0.45) | KDM4EALDH1A1 | |
| SCHEMBL14858605 | 0.82 | LMNA (0.47) | JAK3CYP1A2CYP2C9HTTLMNA | |
| SCHEMBL5237091 | 0.82 | HRH4 (0.47) | HTTPOLB | |
| SCHEMBL5233190 | 0.78 | CYP3A4 (0.39) | JAK2MAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL30719381 | 0.77 | LMNA (0.51) | CYP1A2LMNAMAPTKDM4ETSHR | |
| SCHEMBL30719385 | 0.76 | KDM4E (0.43) | LMNAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL13404374 | 0.74 | IP6K1 (0.50) | IP6K1 | |
| SCHEMBL30719403 | 0.74 | PDE10A (0.44) | — | |
| SCHEMBL311710 | 0.72 | BCHE (0.42) | JAK2JAK3CYP1A2CYP2C19HTT | |
| SCHEMBL30719382 | 0.71 | PDE10A (0.39) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |