Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 5/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237091 | 0.81 | HRH4 (0.47) | — | |
| SCHEMBL30719385 | 0.75 | KDM4E (0.43) | PIK3CAMTORGRIA1 | |
| SCHEMBL21552869 | 0.75 | PDE10A (0.36) | PDE10APIM1PIK3CAMTORGRIA1 | |
| SCHEMBL5233190 | 0.74 | CYP3A4 (0.39) | PDE10A | |
| SCHEMBL30719404 | 0.74 | JAK2 (0.53) | — | |
| SCHEMBL30719381 | 0.73 | LMNA (0.51) | — | |
| SCHEMBL15135220 | 0.72 | HTR2C (0.45) | — | |
| SCHEMBL19035559 | 0.72 | ALDH1A1 (0.50) | PDE10APIM1FGFR1FGFR2FGFR3 | |
| SCHEMBL14858605 | 0.71 | LMNA (0.47) | PIK3CALRRK2 | |
| SCHEMBL23258716 | 0.68 | PIK3CA (0.34) | PDE10APIM1PIK3CAMTORGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |