Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.36 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22532403 | 1.00 | TRPV4 (0.39) | TRPV4SLC13A5SLC13A2SLC13A3PIK3CD | |
| SCHEMBL10289346 | 0.84 | PTGS2 (0.42) | SLC13A5SLC13A2SLC13A3PIK3CDPIK3R1 | |
| SCHEMBL19040355 | 0.83 | TRPV4 (0.40) | TRPV4SLC13A5PTGS2ALPLSMN1; SMN2 | |
| SCHEMBL20304474 | 0.82 | TRPV4 (0.46) | TRPV4PIK3CACCR4ALPLNFE2L2 | |
| SCHEMBL25226442 | 0.81 | APLNR (0.35) | TRPV4PTGS2CCR9ALDH1A1 | |
| SCHEMBL27103224 | 0.81 | MEN1 (0.41) | TRPV4CCR4ALPLSMN1; SMN2 | |
| SCHEMBL22532346 | 0.81 | TRPV4 (0.38) | TRPV4PIK3CACCR4ALPLSCN9A | |
| SCHEMBL11918252 | 0.79 | TSHR (0.43) | SLC13A5SLC13A2SLC13A3PIK3CDPIK3R1 | |
| SCHEMBL31535985 | 0.78 | PTGS2 (0.40) | TRPV4PIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22531857 | 0.77 | TRPV4 (0.44) | TRPV4CCR4ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-4554934-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |