Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548597 | 0.85 | PTGS2 (0.46) | PTGS2ALPLPIK3CDPIK3R1PIK3CA | |
| SCHEMBL19446249 | 0.81 | PTGS2 (0.38) | PTGS2ALPLALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL20304474 | 0.78 | TRPV4 (0.46) | ALPLTRPV4CCR4PIK3CANFE2L2 | |
| SCHEMBL22532403 | 0.78 | TRPV4 (0.39) | PTGS2ALPLTRPV4CCR4ALDH1A1 | |
| SCHEMBL30719557 | 0.78 | TRPV4 (0.39) | PTGS2ALPLTRPV4CCR4ALDH1A1 | |
| SCHEMBL22532346 | 0.77 | TRPV4 (0.38) | ALPLTRPV4CCR4KDM4EPIK3CA | |
| SCHEMBL27103224 | 0.77 | MEN1 (0.41) | ALPLTRPV4CCR4 | |
| SCHEMBL26623958 | 0.75 | MAPK1 (0.41) | ALPLKDM4EALDH1A1CA12CA1 | |
| SCHEMBL30642556 | 0.75 | MAPK1 (0.41) | ALPLKDM4EALDH1A1CA12CA1 | |
| SCHEMBL10332075 | 0.74 | SMN1; SMN2 (0.39) | PTGS2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | PTGS2 3930/4885ALPL 4462/4885TRPV4 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.