Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 12/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720013 | 0.88 | PARP1 (0.47) | PARP1PARP10PARP11PIM1P2RX7 | |
| SCHEMBL30104836 | 0.83 | PARP1 (0.38) | PARP1PARP10PARP11PIM1PSEN1 | |
| SCHEMBL24640536 | 0.74 | CDK4 (0.42) | PARP1P2RX7 | |
| SCHEMBL24640571 | 0.74 | PARP1 (0.47) | PARP1PARP10PARP11P2RX7 | |
| SCHEMBL30104820 | 0.74 | ADRB1 (0.35) | — | |
| SCHEMBL30104783 | 0.68 | POLB (0.32) | — | |
| SCHEMBL24639703 | 0.66 | HTR2C (0.43) | PARP1PARP10PARP11PSEN1PSEN2 | |
| SCHEMBL24640292 | 0.64 | OGA (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31244671 | 0.63 | HTR2A (0.36) | — | |
| SCHEMBL30104795 | 0.63 | PSEN1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |