SCHEMBL30720445 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CHRNB2	P17787	6/20	0.45

▸	CHRNA4	P43681	6/20	0.45

▸	CYP2A6	P11509	3/20	0.42

▸	CYP3A4	P08684	2/20	0.42

▸	HTT	P42858	2/20	0.40

▸	CHRNA7	P36544	2/20	0.40

▸	CHRNA1	P02708	1/20	0.40

▸	CHRNG	P07510	1/20	0.40

▸	CHRNB1	P11230	1/20	0.40

▸	CHRNB4	P30926	1/20	0.40

▸	CHRNA3	P32297	1/20	0.40

▸	CHRND	Q07001	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	MAPK1	P28482	1/20	0.40

▸	CYP2E1	P05181	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6304342	0.78	TP53 (0.48)	CHRNB2CHRNA4CYP3A4CHRNA7CHRNA3
SCHEMBL44773	0.78	TP53 (0.48)	CHRNB2CHRNA4CYP3A4CHRNA7CHRNA3
SCHEMBL28115620	0.71	HTT (0.41)	CHRNB2CHRNA4CYP2A6CYP3A4HTT
SCHEMBL4076888	0.70	CHRNB2 (0.53)	CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL1171348	0.69	CHRNB2 (0.61)	CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL24405651	0.69	CHRNB2 (0.49)	CHRNB2CHRNA4
SCHEMBL29366505	0.69	CYP2A6 (0.44)	CHRNB2CHRNA4CYP2A6CYP3A4HTT
SCHEMBL27762324	0.69	ALOX5 (0.46)	CYP3A4HTTMAPT
SCHEMBL8746704	0.69	ADRB1 (0.46)	MAPT
SCHEMBL161236	0.68	CHRNB2 (0.76)	CHRNB2CHRNA4CHRNA7CHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024012496-A1	CANNABINOID RECEPTOR COMPOUND AND USE THEREOF	长春金赛药业有限责任公司	2024-01-18	—	—	WO	disclosed