Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.42 |
| ▸ | REN | P00797 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | CTSE | P14091 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427600 | 0.83 | BDKRB2 (0.43) | ACERENOPRM1OPRD1BDKRB2 | |
| SCHEMBL29355029 | 0.81 | CAPN1 (0.46) | OPRM1OPRD1CTSDCTSESTAT3 | |
| SCHEMBL29565172 | 0.81 | GRB2 (0.43) | ACERENOPRM1OPRD1CTSD | |
| SCHEMBL29512229 | 0.81 | BDKRB2 (0.44) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL27404602 | 0.79 | CTSD (0.41) | ACERENCTSDCTSESTAT3 | |
| SCHEMBL27317324 | 0.79 | CTSD (0.41) | ACERENCTSDCTSESTAT3 | |
| SCHEMBL8429429 | 0.79 | CXCL8 (0.46) | BDKRB2 | |
| SCHEMBL29801911 | 0.79 | ACE (0.52) | ACEF2 | |
| SCHEMBL29592022 | 0.78 | ACE (0.47) | ACERENSTAT3KDM4EF2 | |
| SCHEMBL27410828 | 0.78 | CTSD (0.39) | ACERENCTSDCTSESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402256-A | Protein dimers consisting of GLP-1 and EGF (A) analogues | 乐普（北京）医疗器械股份有限公司 | 2024-01-16 | — | — | CN | disclosed |