SCHEMBL27410828

SCHEMBL27410828

CCC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTSD P07339 9/20 0.39
▸ CTSE P14091 9/20 0.39
▸ STAT3 P40763 2/20 0.36
▸ ACE P12821 4/20 0.35
▸ REN P00797 2/20 0.35
▸ BACE1 P56817 5/20 0.35
▸ AGTR1 P30556 1/20 0.35
▸ FAP Q12884 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ NAA50 Q9GZZ1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27317324 0.90 CTSD (0.41) CTSDCTSESTAT3ACEREN
SCHEMBL27404602 0.82 CTSD (0.41) CTSDCTSESTAT3ACEREN
SCHEMBL27404606 0.79 CTSD (0.38) CTSDCTSESTAT3ACEREN
SCHEMBL30721557 0.78 ACE (0.42) CTSDCTSESTAT3ACEREN
SCHEMBL27317143 0.77 CTSD (0.38) CTSDCTSESTAT3ACEREN
SCHEMBL29512229 0.72 BDKRB2 (0.44) —
SCHEMBL27404477 0.71 ACE (0.35) CTSDCTSESTAT3ACEREN
SCHEMBL30360330 0.71 REN (0.51) ACERENLMNA
SCHEMBL30844309 0.71 GRB2 (0.54) CTSDCTSESTAT3BACE1FAP
SCHEMBL29630700 0.70 GRB2 (0.44) CTSDCTSESTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209028-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209028-A1 CNP COMPOUNDS NPPA, NPR1, NPR3 CTSD 876/4885CTSE 607/4885STAT3 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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