Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411210 | 0.78 | AADAT (0.36) | AADATMEN1KMT2AMAPTTLR9 | |
| SCHEMBL27451950 | 0.76 | MEN1 (0.44) | AADATMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28878339 | 0.73 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL19410674 | 0.67 | HTR2A (0.45) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28153014 | 0.66 | CES2 (0.50) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31124667 | 0.61 | MEN1 (0.35) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9903242 | 0.60 | OPRM1 (0.44) | AADATMEN1KMT2AMAPTTLR9 | |
| SCHEMBL29620057 | 0.60 | AADAT (0.35) | AADATMEN1KMT2AMAPTTLR9 | |
| SCHEMBL22631177 | 0.58 | AADAT (0.58) | AADATMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6902840 | 0.58 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197118-B | Synthesis method of 3, 3-disubstituted vulcanized oxindole derivative | 贵州医科大学 | 2024-01-23 | — | — | CN | disclosed |