Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723308 | 0.92 | GAA (0.39) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL30723298 | 0.90 | SMN1; SMN2 (0.43) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL30723299 | 0.88 | ATM (0.46) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL30723329 | 0.88 | ALDH1A1 (0.45) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL30723337 | 0.88 | KMT2A (0.36) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL30723297 | 0.87 | ALDH1A1 (0.47) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL30723316 | 0.87 | ALDH1A1 (0.41) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL30723314 | 0.86 | ACHE (0.54) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL30723323 | 0.83 | MAPK1 (0.48) | GAAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL30723312 | 0.83 | SMN1; SMN2 (0.39) | RAB9ASMN1; SMN2BCHEACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |