Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723298 | 0.90 | SMN1; SMN2 (0.43) | ATMMAPTALDH1A1KDM4EGAA | |
| SCHEMBL30723318 | 0.88 | KMT2A (0.43) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL30723329 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30723297 | 0.87 | ALDH1A1 (0.47) | ATMMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL30723314 | 0.86 | ACHE (0.54) | ATMMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL30723337 | 0.84 | KMT2A (0.36) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL30723323 | 0.83 | MAPK1 (0.48) | ALDH1A1KDM4EGAASMN1; SMN2CYP1A1 | |
| SCHEMBL29152982 | 0.82 | HSD17B10 (0.45) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL30723308 | 0.82 | GAA (0.39) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL30723322 | 0.80 | MAPT (0.36) | ATMMAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |