Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TNF | P01375 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723337 | 0.87 | KMT2A (0.36) | MAPK1SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL30723297 | 0.86 | ALDH1A1 (0.47) | MAPK1TSHRSMN1; SMN2LMNAKDM4E | |
| SCHEMBL30723298 | 0.85 | SMN1; SMN2 (0.43) | MAPK1TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30723318 | 0.83 | KMT2A (0.43) | TSHRSMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL30723329 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2LMNAKDM4ECYP1A1CYP1B1 | |
| SCHEMBL30723299 | 0.83 | ATM (0.46) | SMN1; SMN2LMNAKDM4ECYP1A1CYP1B1 | |
| SCHEMBL30723308 | 0.83 | GAA (0.39) | TSHRKDM4EALDH1A1GAA | |
| SCHEMBL29152982 | 0.83 | HSD17B10 (0.45) | TSHRSMN1; SMN2LMNAKDM4ECYP1A1 | |
| SCHEMBL30723314 | 0.82 | ACHE (0.54) | TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30723313 | 0.82 | CYP1A1 (0.43) | MAPK1TNFSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |