Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723314 | 0.90 | ACHE (0.54) | ACHEBCHEL3MBTL1TSHRALDH1A1 | |
| SCHEMBL29152960 | 0.89 | ACHE (0.62) | ACHEBCHEL3MBTL1ALDH1A1LMNA | |
| SCHEMBL30723321 | 0.87 | ACHE (0.53) | ACHEBCHETSHRALDH1A1LMNA | |
| SCHEMBL30723312 | 0.85 | SMN1; SMN2 (0.39) | ACHEBCHELMNASMN1; SMN2 | |
| SCHEMBL30723301 | 0.84 | BCHE (0.39) | ACHEBCHE | |
| SCHEMBL30723310 | 0.80 | RAB9A (0.40) | L3MBTL1ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL30723298 | 0.78 | SMN1; SMN2 (0.43) | ACHEBCHEL3MBTL1TSHRALDH1A1 | |
| SCHEMBL30723297 | 0.78 | ALDH1A1 (0.47) | L3MBTL1TSHRALDH1A1LMNAATM | |
| SCHEMBL30723329 | 0.76 | ALDH1A1 (0.45) | ACHEBCHEL3MBTL1ALDH1A1LMNA | |
| SCHEMBL30723318 | 0.76 | KMT2A (0.43) | ACHEBCHETSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |