Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 4/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235384 | 0.79 | NOS3 (0.41) | NPC1RAB9ANOS3NOS2NOS1 | |
| SCHEMBL22234884 | 0.73 | LTA4H (0.54) | SCN9ANPC1RAB9AEDNRAMAPT | |
| SCHEMBL25254061 | 0.70 | MBOAT4 (0.32) | PDE8AMAPTGSK3B | |
| SCHEMBL30323804 | 0.70 | NOS3 (0.39) | NPC1RAB9ANOS3NOS2NOS1 | |
| SCHEMBL15467137 | 0.70 | NOS3 (0.39) | NPC1RAB9ANOS3NOS2NOS1 | |
| SCHEMBL28163267 | 0.70 | NOS2 (0.39) | NPC1RAB9ANOS3NOS2NOS1 | |
| SCHEMBL29745025 | 0.69 | NOS3 (0.52) | NPC1RAB9AMAPTNOS3NOS2 | |
| SCHEMBL2954177 | 0.69 | NOS3 (0.52) | NPC1RAB9AMAPTNOS3NOS2 | |
| SCHEMBL31602251 | 0.69 | NOS2 (0.42) | NPC1RAB9ANOS3NOS2NOS1 | |
| SCHEMBL9984313 | 0.68 | SMN1; SMN2 (0.47) | MAPTNOS3NOS2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292375-B | Substituted alkoxypyridinyl indole sulfonamides | 优时比制药有限公司 | 2023-12-05 | — | — | CN | disclosed |