Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.48 |
| ▸ | MAOA | P21397 | 9/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769328 | 0.94 | MPO (0.46) | MAOBMAOAELANEHRH3MPO | |
| SCHEMBL30769413 | 0.84 | MAOB (0.48) | MAOBMAOAELANEHRH3MPO | |
| SCHEMBL5851783 | 0.83 | MAOB (0.55) | MAOBMAOAHRH3ESR1MAPT | |
| SCHEMBL30723922 | 0.80 | MAOB (0.50) | MAOBMAOAHRH3ESR1CYP24A1 | |
| SCHEMBL30768559 | 0.80 | MAOB (0.41) | MAOBMAOAHRH3ESR1CYP24A1 | |
| SCHEMBL30724068 | 0.80 | ESR1 (0.60) | MAOBMAOAESR1 | |
| SCHEMBL23297253 | 0.78 | MPO (0.50) | MAOBMAOAELANEHRH3MPO | |
| SCHEMBL30769016 | 0.78 | MAOB (0.44) | MAOBMAOAHRH3ESR1CYP24A1 | |
| SCHEMBL30769201 | 0.77 | EBP (0.52) | MAOBMAOAHRH3ESR1CYP24A1 | |
| SCHEMBL23740291 | 0.75 | MPO (0.49) | MAOBMAOAELANEMPOBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |