Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.41 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723922 | 0.94 | MAOB (0.50) | MAOBMAOACYP24A1CYP27A1HRH3 | |
| SCHEMBL30769201 | 0.86 | EBP (0.52) | MAOBMAOACYP24A1HRH3ESR1 | |
| SCHEMBL23297257 | 0.84 | EBP (0.51) | MAOBMAOACYP27A1HRH3ESR1 | |
| SCHEMBL30724068 | 0.82 | ESR1 (0.60) | MAOBMAOAESR1EBPSIGMAR1 | |
| SCHEMBL30768559 | 0.81 | MAOB (0.41) | MAOBMAOACYP24A1HRH3ESR1 | |
| SCHEMBL30769328 | 0.80 | MPO (0.46) | MAOBMAOACYP24A1HRH3BCHE | |
| SCHEMBL30723754 | 0.78 | MAOB (0.48) | MAOBMAOACYP24A1HRH3ESR1 | |
| SCHEMBL5852029 | 0.76 | MAOB (0.57) | MAOBMAOAHRH3ESR1EBP | |
| SCHEMBL30746228 | 0.75 | MAOA (0.36) | MAOBMAOAHRH3 | |
| SCHEMBL27264109 | 0.75 | MAOA (0.36) | MAOBMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |