Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885770 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL30802436 | 0.76 | CDK1 (0.50) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL30745641 | 0.76 | PKN1 (0.47) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL30724462 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL20588653 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL31095354 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL1458735 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1HSD17B10KDM4E | |
| SCHEMBL30717946 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL31472839 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDTP53L3MBTL1MEN1 | |
| SCHEMBL18706180 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDTP53L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11878978-B1 | Pyrrolo[2,3-c]quinoline compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11878978-B1 | Pyrrolo[2,3-c]quinoline compounds as CK2 inhibitors | CSNK2A3, SKP2, CKS2 | ALDH1A1 4762/4885HPGD 3830/4885TP53 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.