Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686842 | 0.77 | ALDH1A1 (0.59) | PKN1PKN2IMPDH2SIRT2SIRT1 | |
| SCHEMBL30724459 | 0.76 | ALDH1A1 (0.45) | IMPDH2SIRT2SIRT1SIRT3ALDH1A1 | |
| SCHEMBL30824330 | 0.75 | KDM4E (0.50) | PKN1PKN2IMPDH2HCRTR1ALDH1A1 | |
| SCHEMBL30815988 | 0.75 | MMP13 (0.47) | PKN1PKN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL30802436 | 0.74 | CDK1 (0.50) | PKN1PKN2SIRT2SIRT1SIRT3 | |
| SCHEMBL30885770 | 0.73 | ALDH1A1 (0.48) | PKN1PKN2IMPDH2SIRT2SIRT1 | |
| SCHEMBL30833239 | 0.72 | MMP13 (0.47) | PKN1PKN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL30776676 | 0.72 | CDK1 (0.48) | PKN1PKN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL30776675 | 0.72 | CDK1 (0.48) | PKN1PKN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL26976050 | 0.72 | MMP13 (0.47) | PKN1PKN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884668-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[2,3-c]quinolines as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884668-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[2,3-c]quinolines as CK2 inhibitors | CSNK1A1L, CCNL2, CDKL3 | PKN1 324/4885PKN2 97/4885IMPDH2 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.