Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885770 | 0.84 | ALDH1A1 (0.48) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL30779339 | 0.84 | MMP13 (0.47) | CDK1CCNB1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL27088124 | 0.81 | MMP13 (0.47) | CDK1CCNB1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL31095354 | 0.80 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL20588653 | 0.80 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL30802529 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL1458735 | 0.76 | ALDH1A1 (0.58) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL31472839 | 0.76 | ALDH1A1 (0.50) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL30724459 | 0.76 | ALDH1A1 (0.45) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL18706180 | 0.75 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970496-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | King Faisal University (SA) | 2024-04-30 | — | — | US | disclosed |
| US-11958851-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | King Faisal University (SA) | 2024-04-16 | — | — | US | disclosed |
| US-11945818-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | King Faisal University (SA) | 2024-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970496-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | CSNK2A3, CSNK2A1, CSNK1G2 | CDK1 20/4885CCNB1 228/4885SIRT2 2668/4885 |
| US-11945818-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | CSNK2A3, CSNK2A1, CSNK2A2 | CDK1 19/4885CCNB1 260/4885SIRT2 2019/4885 |
| US-11958851-B1 | Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors | SKP2, CSNK2A3, CKS2 | CDK1 20/4885CCNB1 319/4885SIRT2 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.