SCHEMBL30724665

SCHEMBL30724665

NC(=O)c1ccc(-c2ccc3ccccc3c2)c(C(N)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 4/20 0.52
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
GSTP1 P09211 1/20 0.47
CTRB1 P17538 1/20 0.45
LCK P06239 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
PLAU P00749 2/20 0.44
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
CDC7 O00311 1/20 0.43
AR P10275 2/20 0.43
ACMSD Q8TDX5 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5842776 0.88 CHEK2 (0.52) CHEK2SLC6A2SLC6A4SLC6A3GSTP1
SCHEMBL30397343 0.88 CHEK2 (0.52) CHEK2SLC6A2SLC6A4SLC6A3GSTP1
SCHEMBL29403578 0.84 BCAT2 (0.49) CHEK2BCAT2
SCHEMBL31621280 0.83 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3GSTP1HDAC4
SCHEMBL31621279 0.83 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3GSTP1HDAC4
SCHEMBL22289582 0.83 CHEK2 (0.51) CHEK2GSTP1CTRB1LCKCES2
SCHEMBL944091 0.82 BCAT2 (0.63) CHEK2BCAT2
SCHEMBL546633 0.79 CES2 (0.68) CHEK2LCKCES2CES1PLAU
SCHEMBL29462782 0.79 CES2 (0.68) CHEK2LCKCES2CES1PLAU
SCHEMBL26903783 0.79 CES2 (0.68) CHEK2LCKCES2CES1PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117175142-A Separator for nonaqueous electrolyte secondary battery 住友化学株式会社 2023-12-05 CN disclosed