SCHEMBL944091

SCHEMBL944091

NC(=O)c1ccc(-c2ccccc2)c(C(N)=O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 2/20 0.63
CHEK2 O96017 3/20 0.49
MKNK1 Q9BUB5 2/20 0.49
MKNK2 Q9HBH9 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
IKBKB O14920 3/20 0.47
DHODH Q02127 2/20 0.47
CASP1 P29466 1/20 0.46
CHUK O15111 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5215160 0.91 BCAT2 (0.61) BCAT2POLBIKBKBDHODHCASP1
SCHEMBL3265708 0.85 BCAT2 (0.63) BCAT2CHEK2MKNK1MKNK2L3MBTL1
SCHEMBL30903715 0.85 L3MBTL1 (0.52) BCAT2CHEK2MKNK1MKNK2L3MBTL1
SCHEMBL2026663 0.85 L3MBTL1 (0.52) BCAT2CHEK2MKNK1MKNK2L3MBTL1
SCHEMBL29403578 0.84 BCAT2 (0.49) BCAT2CHEK2MKNK1MKNK2L3MBTL1
Hydrochloric Acid SCHEMBL28812686 0.83 CHEK2 (0.50) BCAT2CHEK2MKNK1MKNK2L3MBTL1
SCHEMBL6175390 0.82 CYP1A2 (0.57) BCAT2L3MBTL1TSHRCYP2C19HSD17B10
SCHEMBL30724665 0.82 CHEK2 (0.52) BCAT2CHEK2
SCHEMBL3781170 0.81 MKNK1 (0.53) BCAT2CHEK2MKNK1MKNK2L3MBTL1
SCHEMBL3794623 0.81 BCAT2 (0.63) BCAT2CHEK2MKNK1POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114502621-A Polymer derived elastic heat spreader films 环球石墨烯集团公司 2022-05-13 CN claimed
CN-112661954-A Star polyamide and application thereof 中国石油化工股份有限公司 2021-04-16 CN claimed
WO-2021055304-A1 POLYMER-DERIVED ELASTIC HEAT SPREADER FILMS GLOBAL GRAPHENE GROUP, INC. (US) 2021-03-25 WO claimed
US-20210079282-A1 POLYMER-DERIVED ELASTIC HEAT SPREADER FILMS NANOTEK INSTRUMENTS, INC. (US) 2021-03-18 US claimed
EP-2847437-A1 WEAR RESISTANT ARTICLE E. I. Du Pont de Nemours and Company (US) 2015-03-18 EP claimed
EP-2847436-A1 WEAR RESISTANT TURBINE FAN BLADE E. I. Du Pont de Nemours and Company (US) 2015-03-18 EP claimed
WO-2013169272-A1 WEAR RESISTANT ARTICLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-14 WO claimed
US-20130302173-A1 WEAR RESISTANT TURBINE FAN BLADE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-14 US claimed
US-20130302170-A1 ROTOR DISK AND ROTOR ASSEMBLY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-14 US claimed
US-20130303413-A1 WEAR RESISTANT ARTICLE E. I. DU PONT DE NEMOURS AND COMPANY (DE) 2013-11-14 US claimed
EP-0487568-A4 NOMEX PRINTING. BURLINGTON INDUSTRIES INC (US) 1992-04-14 EP claimed
US-5091025-A Heat treatment of pyropolymer in inert gas MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-02-25 US claimed
WO-1991002837-A1 NOMEX PRINTING BURLINGTON INDUSTRIES, INC. (US) 1991-03-07 WO claimed
EP-0397152-A1 Process for making a graphite film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-11-14 EP claimed
EP-0059867-B1 THIN INSULATING SHEET MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1985-09-11 EP claimed
EP-0059866-B1 THIN INSULATING SHEET MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1985-09-04 EP claimed
US-4536437-A MULTILAYER-POLYAMIDE AND CARBON BLACK BASE, AND INK LAYER CONTAINING RESIN RICOH COMPANY, LTD. (JP) 1985-08-20 US claimed
US-4448921-A WITH AROMATIC POLYAMIDE OR POLYAMIDEIMIDE MITSUBISHI PAPER MILLS, LTD. (JP) 1984-05-15 US claimed
US-4399190-A POLYIMIDE, POLYAMIDE, POLYPARABANIC ACID OR POLYESTER FILMS IMPREGNATED AND MELT-BONDED TO POLYMER DIBRILS MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1983-08-16 US claimed
US-4399191-A POLYMER FILM MELT BONDED TO POLMER FIBRILS MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1983-08-16 US claimed