SCHEMBL30724686

SCHEMBL30724686

CS(=O)(=O)c1cccc(CNc2ncccn2)c1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 6/20 0.56
PTK2 Q05397 7/20 0.51
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PI4KB Q9UBF8 2/20 0.44
GPR39 O43194 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28651170 0.87 VNN1 (0.50) VNN1PTK2ALDH1A1GAAHSD17B10
SCHEMBL30724687 0.82 GPR39 (0.56) VNN1GPR39
SCHEMBL18757140 0.80 VNN1 (0.50) VNN1PTK2
SCHEMBL10054967 0.79 ALDH1A1 (0.52) ALDH1A1
SCHEMBL8278304 0.78 ALDH1A1 (0.51) PTK2ALDH1A1GAAHSD17B10
SCHEMBL14805811 0.78 ALDH1A1 (0.48) VNN1PTK2ALDH1A1GAAHSD17B10
SCHEMBL14025590 0.77 TAS2R14 (0.50) ALDH1A1
SCHEMBL19422111 0.77 ALDH1A1 (0.54) VNN1ALDH1A1GAAHSD17B10
SCHEMBL14554911 0.75 CYP1A2 (0.51) VNN1ALDH1A1HSD17B10
SCHEMBL30468404 0.74 PTK2 (0.51) VNN1PTK2PI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396471-A Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same 株式会社次代生物科学 2024-01-12 CN disclosed