Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724705 | 0.90 | LMNA (0.43) | LMNAMMP12MMP9MMP8KDM4E | |
| SCHEMBL30724701 | 0.89 | LMNA (0.48) | LMNAMMP12MMP9MMP8KDM4E | |
| SCHEMBL30918324 | 0.83 | LMNA (0.42) | LMNAMMP12MMP9MMP8PKM | |
| SCHEMBL27428949 | 0.83 | LMNA (0.42) | LMNAMMP12MMP9MMP8PKM | |
| SCHEMBL27428883 | 0.82 | LMNA (0.41) | LMNAMMP12MMP9MMP8PKM | |
| SCHEMBL30724712 | 0.82 | LMNA (0.53) | LMNAKDM4EPKMKMT2ANAPRT | |
| SCHEMBL30724708 | 0.81 | BACE1 (0.45) | LMNAMMP12MMP9MMP8KISS1R | |
| SCHEMBL30946749 | 0.81 | CTSC (0.50) | MMP9MMP8PKMMMP14 | |
| SCHEMBL27428938 | 0.77 | KISS1R (0.43) | LMNAMMP12MMP9MMP8NLRP3 | |
| SCHEMBL27428881 | 0.76 | LMNA (0.41) | LMNAMMP12MMP9MMP8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547337-A1 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | Sanofi (FR) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024003313-A9 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2025-03-20 | — | — | WO | disclosed |
| WO-2024003313-A1 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2024-01-04 | — | — | WO | disclosed |