Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724710 | 0.89 | LMNA (0.44) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL30724705 | 0.88 | LMNA (0.43) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL4436681 | 0.84 | GPR132 (0.51) | MMP9MMP8CTRB1TBXAS1KDM4E | |
| SCHEMBL30724712 | 0.81 | LMNA (0.53) | LMNAPKMKMT2ATBXAS1NAPRT | |
| SCHEMBL27428949 | 0.81 | LMNA (0.42) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL30918324 | 0.81 | LMNA (0.42) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL27428883 | 0.80 | LMNA (0.41) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL30724708 | 0.79 | BACE1 (0.45) | LMNAMMP9MMP8MMP12 | |
| SCHEMBL27428881 | 0.78 | LMNA (0.41) | LMNAMMP9MMP8MMP12PKM | |
| SCHEMBL30946749 | 0.78 | CTSC (0.50) | MMP9MMP8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547337-A1 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | Sanofi (FR) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024003313-A9 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2025-03-20 | — | — | WO | disclosed |
| WO-2024003313-A1 | NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2024-01-04 | — | — | WO | disclosed |