Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045646 | 1.00 | AKR1B1 (0.57) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL9781384 | 0.89 | AKR1B1 (0.61) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL27682579 | 0.84 | HSD17B1 (0.47) | AKR1B1ALOX5MEN1MAPTKMT2A | |
| SCHEMBL27701864 | 0.82 | ALOX5 (0.48) | AKR1B1GABRA1GABRB2ALOX5MEN1 | |
| SCHEMBL28768894 | 0.82 | MEN1 (0.43) | AKR1B1ALOX5MEN1KMT2APNMT | |
| SCHEMBL28847551 | 0.81 | APP (0.53) | ALOX5GAAMAPTPNMTMGAM | |
| SCHEMBL30036609 | 0.81 | APP (0.53) | ALOX5GAAMAPTPNMTMGAM | |
| SCHEMBL30215909 | 0.80 | ALOX5 (0.40) | AKR1B1ALOX5PNMT | |
| SCHEMBL27682544 | 0.80 | ALOX5 (0.40) | AKR1B1ALOX5PNMT | |
| SCHEMBL5263845 | 0.79 | AKR1B1 (0.44) | AKR1B1GABRA1GABRB2CNR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153658-B1 | CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS | WACKER CHEMIE AG (DE) | 2023-12-06 | — | — | EP | disclosed |