SCHEMBL17045646

SCHEMBL17045646

C=CCc1cc(-c2ccc3c(c2-c2ccc(O)c(CC=C)c2)Cc2ccccc2-3)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.57
GABRA1 P14867 8/20 0.51
GABRB2 P47870 8/20 0.51
CNR2 P34972 3/20 0.49
ALOX5 P09917 3/20 0.49
POLB P06746 2/20 0.49
ACE2 Q9BYF1 2/20 0.49
CNR1 P21554 2/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
GABRB1 P18505 1/20 0.49
RXRA P19793 1/20 0.49
GABRA5 P31644 1/20 0.49
GABRA3 P34903 1/20 0.49
GABRA2 P47869 1/20 0.49
KMT2A Q03164 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49
PNMT P11086 1/20 0.39
MGAM O43451 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30725932 1.00 AKR1B1 (0.57) AKR1B1GABRA1GABRB2CNR2ALOX5
SCHEMBL9781384 0.89 AKR1B1 (0.61) AKR1B1GABRA1GABRB2CNR2ALOX5
SCHEMBL27682579 0.84 HSD17B1 (0.47) AKR1B1ALOX5MEN1MAPTKMT2A
SCHEMBL27701864 0.82 ALOX5 (0.48) AKR1B1GABRA1GABRB2ALOX5MEN1
SCHEMBL28768894 0.82 MEN1 (0.43) AKR1B1ALOX5MEN1KMT2APNMT
SCHEMBL28847551 0.81 APP (0.53) ALOX5GAAMAPTPNMTMGAM
SCHEMBL30036609 0.81 APP (0.53) ALOX5GAAMAPTPNMTMGAM
SCHEMBL30215909 0.80 ALOX5 (0.40) AKR1B1ALOX5PNMT
SCHEMBL27682544 0.80 ALOX5 (0.40) AKR1B1ALOX5PNMT
SCHEMBL5263845 0.79 AKR1B1 (0.44) AKR1B1GABRA1GABRB2CNR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105742194-B The interim joint method of chip and LED reverse mounting type manufacturing method 信越化学工业株式会社 2019-08-27 CN disclosed
US-9725590-B2 Epoxy compound having alkoxysilyl group, method for preparing the same, composition including the same, cured product made from the composition, and use of the composition KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2017-08-08 US disclosed
EP-2933257-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING SAME, COMPOSITION COMPRISING SAME, CURED PRODUCT MADE THEREFROM, AND USE THEREOF Korea Institute Of Industrial Technology (KR) 2015-10-21 EP disclosed
US-20150247033-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING THE SAME, COMPOSITION INCLUDING THE SAME, CURED PRODUCT MADE FROM THE COMPOSITION, AND USE OF THE COMPOSITION KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247033-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING THE SAME, COMPOSITION INCLUDING THE SAME, CURED PRODUCT MADE FROM THE COMPOSITION, AND USE OF THE COMPOSITION ESD, ELL, ALOX5 AKR1B1 1231/4885GABRA1 3097/4885GABRB2 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.