SCHEMBL27701864

SCHEMBL27701864

CCCc1cc(-c2ccc3c(c2-c2ccc(O)c(CCC)c2)Cc2ccccc2-3)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
PNMT P11086 1/20 0.40
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
HSD17B1 P14061 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
AKR1B1 P15121 1/20 0.35
PGR P06401 1/20 0.35
ELANE P08246 1/20 0.34
CTSG P08311 1/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
DRD2 P14416 1/20 0.33
APP P05067 1/20 0.33
BACE1 P56817 1/20 0.32
HSP90AA1 P07900 1/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27682544 0.93 ALOX5 (0.40) ALOX5PNMTESR1ESR2HSD17B1
SCHEMBL30215909 0.93 ALOX5 (0.40) ALOX5PNMTESR1ESR2HSD17B1
SCHEMBL27682579 0.90 HSD17B1 (0.47) ALOX5PNMTESR1ESR2HSD17B1
SCHEMBL27737089 0.89 ALOX5 (0.51) ALOX5PNMTESR1ESR2GABRA1
SCHEMBL28768894 0.83 MEN1 (0.43) ALOX5PNMTESR1ESR2AKR1B1
SCHEMBL30725932 0.82 AKR1B1 (0.57) ALOX5PNMTGABRA1GABRB2AKR1B1
SCHEMBL17045646 0.82 AKR1B1 (0.57) ALOX5PNMTGABRA1GABRB2AKR1B1
SCHEMBL30036609 0.82 APP (0.53) ALOX5PNMTNPC1RAB9APGR
SCHEMBL28847551 0.82 APP (0.53) ALOX5PNMTNPC1RAB9APGR
SCHEMBL21295464 0.81 PNMT (0.43) ALOX5PNMTESR1ESR2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107003463-B Phase difference film and its manufacturing method 日东电工株式会社 2019-09-06 CN disclosed
CN-110116493-A The manufacturing method of thin film stretching device and phase-contrast film 日东电工株式会社 2019-08-13 CN disclosed
CN-110103451-A The manufacturing method of thin film stretching device and oriented film 日东电工株式会社 2019-08-09 CN disclosed
CN-110103452-A The manufacturing method of thin film stretching device and phase-contrast film 日东电工株式会社 2019-08-09 CN disclosed
CN-101048679-A Infrared absorbing filter OSAKA GAS CO LTD (JP) 2007-10-03 CN disclosed