Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833037 | 0.87 | LMNA (0.62) | LMNACHRM1CHRM2ADRA2ASLC6A2 | |
| SCHEMBL2552243 | 0.87 | LMNA (0.62) | LMNACHRM1CHRM2ADRA2ASLC6A2 | |
| SCHEMBL20538944 | 0.82 | LMNA (0.43) | LMNACHRM1CHRM2CYP2D6CHRM3 | |
| SCHEMBL6624926 | 0.81 | GLS (0.50) | LMNACYP2D6ADRA1ACYP1A2TSHR | |
| SCHEMBL21644503 | 0.80 | GLS (0.48) | LMNASLC6A2SLC6A4DRD3SLC6A3 | |
| SCHEMBL8938105 | 0.80 | SMN1; SMN2 (0.43) | LMNADRD3SLC6A3CYP2D6HRH1 | |
| SCHEMBL17536560 | 0.78 | SMN1; SMN2 (0.44) | CYP2D6CYP1A2SMN1; SMN2CYP3A4NPSR1 | |
| SCHEMBL10698580 | 0.78 | LMNA (0.48) | LMNACHRM2ADRA2ASLC6A3HTR2B | |
| Diphenhydramine SCHEMBL25268546 | 0.78 | SLC6A2 (0.83) | LMNACHRM1CHRM2ADRA2ASLC6A2 | |
| SCHEMBL7556093 | 0.78 | GLS (0.43) | LMNADRD3SLC6A3CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988124-B | Inhibitor of renal glutaminase allosteric site containing oxygen group element diazole or tetrazole structure | 杭州健昵福生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |