Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL3739485 | 0.82 | MME (0.40) | ALDH1A1MME | |
| SCHEMBL2951352 | 0.82 | ALPI (0.42) | ALDH1A1MME | |
| Toluene SCHEMBL8474940 | 0.77 | MME (0.38) | TDP1POLBKDM4EMME | |
| SCHEMBL488918 | 0.74 | THRB (0.53) | THRBTSHRLMNASMN1; SMN2TDP1 | |
| Methacrylic Acid SCHEMBL28158161 | 0.73 | THRB (0.51) | THRBTSHRLMNASMN1; SMN2TDP1 | |
| SCHEMBL316845 | 0.73 | THRB (0.54) | THRBTSHRLMNASMN1; SMN2TDP1 | |
| SCHEMBL9159591 | 0.73 | THRB (0.54) | THRBTSHRLMNASMN1; SMN2TDP1 | |
| SCHEMBL15639721 | 0.72 | TBXAS1 (0.41) | MME | |
| Methacrylic Acid SCHEMBL8041672 | 0.71 | THRB (0.89) | THRBTSHRLMNATDP1POLB | |
| Acrylic Acid SCHEMBL28848911 | 0.71 | THRB (0.57) | THRBTSHRLMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7789333-B2 | Media mill process | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1440128-B1 | MILL PROCESS WITH CUBIC MEDIA | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1440128-A1 | MILL PROCESS WITH CUBIC MEDIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003040245-A1 | MILL PROCESS WITH CUBIC MEDIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |