Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672550 | 0.87 | MAPT (0.48) | MAPTTSHRGAAMAPK1HSD17B10 | |
| SCHEMBL668473 | 0.86 | GAA (0.49) | MAPTTSHRGAAMAPK1HSD17B10 | |
| SCHEMBL30429212 | 0.86 | GAA (0.49) | MAPTTSHRGAAMAPK1HSD17B10 | |
| SCHEMBL22261474 | 0.82 | SLC6A3 (0.54) | MAPTTSHRGAAHSD17B10SLC6A3 | |
| SCHEMBL30285248 | 0.81 | SLC6A3 (0.60) | MAPTTSHRGAAMAPK1HSD17B10 | |
| SCHEMBL7174241 | 0.81 | SLC6A3 (0.60) | MAPTTSHRGAAMAPK1HSD17B10 | |
| SCHEMBL29041518 | 0.81 | LMNA (0.52) | MAPTTSHRGAAHSD17B10SLC6A3 | |
| SCHEMBL29240004 | 0.78 | SLC6A3 (0.43) | MAPTTSHRGAAMAPK1HSD17B10 | |
| Methyl 2-Methoxybenzoate SCHEMBL29702077 | 0.78 | TSHR (0.69) | MAPTTSHRGAAMAPK1HSD17B10 | |
| Methyl 2-Methoxybenzoate SCHEMBL196037 | 0.78 | TSHR (0.69) | MAPTTSHRGAAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186001-B | AHA1 inhibitor with multiple myeloma-resisting activity and preparation method and application thereof | 南京中医药大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-117186001-A | AHA1 inhibitor with multiple myeloma-resisting activity and preparation method and application thereof | 南京中医药大学 | 2023-12-08 | — | — | CN | disclosed |