SCHEMBL7174241

SCHEMBL7174241

COC(=O)c1ccccc1-c1ccccc1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 5/20 0.60
SLC6A4 P31645 3/20 0.60
TSHR P16473 3/20 0.57
MAPT P10636 3/20 0.57
HSD17B10 Q99714 2/20 0.57
GAA P10253 1/20 0.57
MAPK1 P28482 1/20 0.57
LMNA P02545 1/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 1/20 0.53
SLC6A2 P23975 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CFTR P13569 1/20 0.52
CTSD P07339 1/20 0.51
HTT P42858 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
MAPK10 P53779 1/20 0.51
PTK2B Q14289 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30285248 1.00 SLC6A3 (0.60) SLC6A3SLC6A4TSHRMAPTHSD17B10
Methyl 2-Methoxybenzoate SCHEMBL196037 0.88 TSHR (0.69) SLC6A3SLC6A4TSHRMAPTHSD17B10
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.88 TSHR (0.69) SLC6A3SLC6A4TSHRMAPTHSD17B10
SCHEMBL69464 0.88 SLC6A3 (0.67) SLC6A3SLC6A4TSHRMAPTHSD17B10
Methyl 2-Methoxybenzoate SCHEMBL30744939 0.86 MAPT (0.67) SLC6A3SLC6A4TSHRMAPTHSD17B10
SCHEMBL30285122 0.86 SLC6A3 (0.61) SLC6A3SLC6A4TSHRMAPTHSD17B10
SCHEMBL1638896 0.86 SLC6A3 (0.58) SLC6A3SLC6A4TSHRMAPTHSD17B10
Methyl 2-Methoxybenzoate SCHEMBL5182927 0.85 SLC6A3 (0.66) SLC6A3SLC6A4TSHRMAPTHSD17B10
SCHEMBL7481393 0.84 TSHR (0.63) SLC6A3SLC6A4TSHRMAPTHSD17B10
SCHEMBL1638900 0.84 SLC6A3 (0.61) SLC6A3SLC6A4TSHRMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122221-A1 SIX-MEMBERED CYCLOTHIAZOLE COMPOUND AND USE THEREOF NANJING ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2025-04-17 US disclosed
EP-4464709-A1 SIX-MEMBERED CYCLOTHIAZOLE COMPOUND AND USE THEREOF Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) 2024-11-20 EP disclosed
WO-2023134739-A1 SIX-MEMBERED CYCLOTHIAZOLE COMPOUND AND USE THEREOF 南京再明医药有限公司 2023-07-20 WO disclosed
US-20090298826-A1 NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING (SUBSTITUTED PHENYL OR SUBSTITUTED HETEROCYCLIC) CARBONYLOXY LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS SANTEN PHARMACEUTICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-6558712-B1 Stable, water soluble purified shilajit extract containing sponge like fulvic acid carrier punctured by voids filled by active ingredient NATREON INC. 2003-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122221-A1 SIX-MEMBERED CYCLOTHIAZOLE COMPOUND AND USE THEREOF POLRMT, POLQ, POLH SLC6A3 2878/4885SLC6A4 2448/4885TSHR 4103/4885
US-20090298826-A1 NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING (SUBSTITUTED PHENYL OR SUBSTITUTED HETEROCYCLIC) CARBONYLOXY LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS NR3C1, NR3C2, NR5A1 SLC6A3 1818/4885SLC6A4 2191/4885TSHR 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.