Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 13/20 | 0.77 |
| ▸ | RAB9A | P51151 | 13/20 | 0.77 |
| ▸ | NPC1 | O15118 | 12/20 | 0.77 |
| ▸ | TP53 | P04637 | 9/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.73 |
| ▸ | RELA | Q04206 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428143 | 1.00 | SMN1; SMN2 (0.77) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL7961699 | 0.89 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL14147338 | 0.87 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL16716023 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL12171135 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL5660762 | 0.80 | RAB9A (0.61) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL7958390 | 0.79 | TTR (0.55) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL23288082 | 0.78 | CASP3 (0.71) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL12692348 | 0.78 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL11732877 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377478-A | Methods and compositions for regenerating hair cells in the inner ear of an adult mammal | 麻省眼耳科医院 | 2024-01-09 | — | — | CN | disclosed |