Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.32 |
| ▸ | ELOC | Q15369 | 1/20 | 0.32 |
| ▸ | ELOB | Q15370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725652 | 0.88 | BDKRB2 (0.34) | PPM1DVHLELOCELOB | |
| SCHEMBL9595418 | 0.87 | ABCB1 (0.35) | VHLELOCELOB | |
| SCHEMBL8106554 | 0.87 | ABCB1 (0.35) | VHLELOCELOB | |
| SCHEMBL3470472 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL30729563 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL2634064 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL376587 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL5314317 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL29245844 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL3525995 | 0.86 | PPM1D (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696919-A4 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1696919-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | Incyte Corporation (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005060665-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |