Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159437 | 0.85 | F2RL1 (0.34) | DGAT1NPC1F2RL1 | |
| SCHEMBL15726275 | 0.84 | DGAT1 (0.38) | UCHL1DGAT1ALDH1A1LMNANPC1 | |
| SCHEMBL20642921 | 0.83 | DGAT1 (0.37) | UCHL1DGAT1ALDH1A1LMNAMAPT | |
| SCHEMBL21296472 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL2965865 | 0.79 | CYP2C9 (0.42) | HTTDGAT1ALDH1A1LMNAMAPT | |
| SCHEMBL267991 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL2703787 | 0.77 | LMNA (0.42) | ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL30828686 | 0.77 | LMNA (0.42) | ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL22900570 | 0.76 | DGAT1 (0.35) | UCHL1HTTDGAT1ALDH1A1MAPT | |
| SCHEMBL14972966 | 0.75 | LMNA (0.40) | ALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |