Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553858 | 1.00 | CD38 (0.45) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22553948 | 0.87 | CAMKK2 (0.45) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22553811 | 0.86 | JAK2 (0.46) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22553799 | 0.86 | CD38 (0.42) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22570987 | 0.84 | DYRK1A (0.39) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22553722 | 0.82 | MAP4K1 (0.40) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22553926 | 0.81 | ROCK2 (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22554043 | 0.81 | MAP4K1 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22553899 | 0.80 | NUDT1 (0.46) | CD38PRKAA1NPC1DYRK1ADYRK1B | |
| SCHEMBL22554254 | 0.79 | PRKAB2 (0.41) | CD38PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |