Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26637106 | 1.00 | PTGS2 (0.41) | PTGS2F2PPARAPOLBCYP4F2 | |
| SCHEMBL26636357 | 0.91 | LTA4H (0.43) | F2PPARAPOLBCYP4F2CYP4A11 | |
| SCHEMBL30657231 | 0.91 | LTA4H (0.43) | F2PPARAPOLBCYP4F2CYP4A11 | |
| SCHEMBL30670073 | 0.90 | CYP4F2 (0.39) | F2PPARAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26619309 | 0.90 | CYP4F2 (0.39) | F2PPARAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26635941 | 0.85 | F2 (0.35) | F2PPARAPOLBPPARGPPARD | |
| SCHEMBL30735244 | 0.81 | LMNA (0.34) | F2PPARAPOLBPPARGPPARD | |
| SCHEMBL26639563 | 0.81 | F2 (0.33) | F2PPARAPOLBPPARGPPARD | |
| SCHEMBL26619360 | 0.81 | LMNA (0.34) | F2PPARAPOLBPPARGPPARD | |
| SCHEMBL30657399 | 0.81 | VDR (0.43) | PPARATDP1PPARGPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |