Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615443 | 0.86 | GABRP (0.52) | CYP1A2AURKAGABRPGABRDGABRA1 | |
| SCHEMBL22093416 | 0.80 | MAT2A (0.46) | CYP1A2CYP2C9ALDH1A1MAT2AMEN1 | |
| SCHEMBL22093677 | 0.80 | MAT2A (0.60) | ALDH1A1PARP1MAT2A | |
| SCHEMBL30319853 | 0.80 | MAT2A (0.60) | ALDH1A1PARP1MAT2A | |
| SCHEMBL31361093 | 0.74 | MAT2A (0.39) | HPGDALDH1A1MAT2AMEN1KMT2A | |
| SCHEMBL31140492 | 0.73 | MAT2A (0.43) | ALDH1A1MAT2AMEN1KMT2AL3MBTL1 | |
| SCHEMBL22103088 | 0.73 | MAT2A (0.60) | MAT2A | |
| SCHEMBL31140487 | 0.73 | MAT2A (0.43) | PARP1MAT2AKDM4EMAPT | |
| SCHEMBL31140485 | 0.73 | MAT2A (0.43) | PARP1MAT2AKDM4EMAPT | |
| SCHEMBL31140490 | 0.73 | MAT2A (0.43) | ALDH1A1MAT2AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024002024-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2024-01-04 | — | — | WO | disclosed |