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SCHEMBL30736995

SCHEMBL30736995

CC(C)(C)CC[C@H](NC(=O)c1ccc(Oc2cccc3c(C(=O)NCCCNC(=O)CCOCCOCCOCCOCCNc4ccc([N+](=O)[O-])cc4[N+](=O)[O-])cccc23)nc1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SORT1 Q99523 3/20 0.45
▸ FOLH1 Q04609 10/20 0.43
▸ GRN P28799 2/20 0.43
▸ DGAT1 O75907 6/20 0.39
▸ HCAR3 P49019 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737232 0.88 HCAR3 (0.41) FOLH1DGAT1HCAR3KMT2A
SCHEMBL30737153 0.87 HCAR3 (0.38) FOLH1HCAR3KMT2A
SCHEMBL30737421 0.81 FOLH1 (0.35) FOLH1DGAT1KMT2A
SCHEMBL31646288 0.74 SORT1 (0.43) SORT1FOLH1GRNDGAT1HCAR3
SCHEMBL30737257 0.74 SORT1 (0.66) SORT1GRN
SCHEMBL30737086 0.71 PLK1 (0.38) SORT1KMT2A
SCHEMBL30737297 0.70 SORT1 (0.69) SORT1FOLH1GRN
SCHEMBL30737241 0.69 HDAC3 (0.37) KMT2A
SCHEMBL31646191 0.68 HCAR3 (0.48) HCAR3KMT2A
SCHEMBL31646647 0.67 HCAR3 (0.44) HCAR3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 — — EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 — — WO disclosed