SCHEMBL30737356

SCHEMBL30737356

COC(=O)c1ccc(Oc2cccc(C(=O)OC(C)(C)C)c2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 1/20 0.49
GAA P10253 2/20 0.47
MAPK1 P28482 2/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.45
CASP3 P42574 1/20 0.45
KMT2A Q03164 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
GRN P28799 2/20 0.44
SORT1 Q99523 2/20 0.44
PPARG P37231 2/20 0.43
NR1H2 P55055 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737207 0.89 GRN (0.45) L3MBTL1GAAMAPK1MAPTTDP1
SCHEMBL30737068 0.89 GRN (0.45) L3MBTL1GAAMAPK1MAPTTDP1
SCHEMBL31646829 0.85 L3MBTL1 (0.54) L3MBTL1LMNAGAAMAPK1MAPT
SCHEMBL30737193 0.84 LMNA (0.51) L3MBTL1LMNAGAAMAPK1MAPT
SCHEMBL30737060 0.83 L3MBTL1 (0.52) L3MBTL1LMNAGAAMAPK1MAPT
SCHEMBL30737432 0.81 CA12 (0.44) L3MBTL1LMNACASP3SENP7GRN
SCHEMBL31646813 0.80 LOX (0.47) L3MBTL1GAAMAPK1MAPTTDP1
SCHEMBL31646343 0.80 GRN (0.52) L3MBTL1GAAMAPK1MAPTTDP1
SCHEMBL30737387 0.80 SORT1 (0.65) L3MBTL1LMNAGAAMAPK1MAPT
SCHEMBL30737138 0.80 SORT1 (0.65) L3MBTL1LMNAGAAMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed