Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25020926 | 0.86 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL16614205 | 0.81 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL23976511 | 0.80 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL4283172 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL4288489 | 0.79 | MAPT (0.60) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL22775284 | 0.79 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL19851616 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL22775067 | 0.79 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL22648389 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT | |
| SCHEMBL22648390 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008196-A1 | CLASS OF AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2024-01-11 | — | — | WO | disclosed |