Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | WNT1 | P04628 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533437 | 0.80 | L3MBTL1 (0.62) | MAPTHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL30738415 | 0.79 | SMN1; SMN2 (0.69) | MAPTHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4288020 | 0.78 | KMT2A (0.62) | HTTSMN1; SMN2ALDH1A1L3MBTL1TAS2R8 | |
| SCHEMBL13479586 | 0.77 | MAPT (0.64) | MAPTHTTSMN1; SMN2ALDH1A1LMNA | |
| Methyl Alcohol SCHEMBL4593446 | 0.77 | MAPT (0.93) | MAPTHTTALDH1A1L3MBTL1LMNA | |
| SCHEMBL4285505 | 0.77 | ALDH1A1 (0.64) | MAPTHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3061430 | 0.77 | MAPT (1.00) | MAPTHTTLMNAGAARAB9A | |
| SCHEMBL25020926 | 0.76 | ALDH1A1 (0.73) | MAPTHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27689202 | 0.75 | MAPT (0.96) | MAPTHTTLMNAGAARAB9A | |
| SCHEMBL6966254 | 0.75 | EGFR (0.70) | MAPTHTTSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | MAPT 868/4885HTT 4201/4885SMN1; SMN2 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.