Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25020926 | 0.84 | ALDH1A1 (0.73) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL23976511 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL30738415 | 0.81 | SMN1; SMN2 (0.69) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL22648389 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL19851616 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL22775067 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL22775284 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL22774233 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL4730942 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL6971648 | 0.78 | HTT (0.64) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850203-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850203-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850203-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | ALDH1A1 4720/4885HTT 138/4885SMN1; SMN2 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.