SCHEMBL30739629

SCHEMBL30739629

Nc1ccc(F)c(C(=O)NCCCCl)c1F

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
RECQL P46063 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HDAC3 O15379 6/20 0.37
HDAC1 Q13547 6/20 0.37
MAOB P27338 2/20 0.36
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TP53 P04637 1/20 0.36
MDM2 Q00987 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20050672 1.00 HTT (0.45) HTTNPC1RAB9ARECQLALDH1A1
SCHEMBL20051588 0.83 NPC1 (0.42) HTTNPC1RAB9ARECQLALDH1A1
SCHEMBL30739605 0.83 NPC1 (0.42) HTTNPC1RAB9ARECQLALDH1A1
SCHEMBL20051091 0.82 GABRG2 (0.41) HTTNPC1RAB9ARECQLALDH1A1
SCHEMBL30739798 0.82 GABRG2 (0.41) HTTNPC1RAB9ARECQLALDH1A1
SCHEMBL20050366 0.79 CFTR (0.43) HTTNPC1RAB9AALDH1A1HDAC3
SCHEMBL20051088 0.78 PRKCZ (0.37) HTTNPC1RAB9AALDH1A1HDAC1
SCHEMBL30739958 0.78 PRKCZ (0.37) HTTNPC1RAB9AALDH1A1HDAC1
SCHEMBL29241617 0.78 ALDH1A1 (0.42) HTTNPC1RAB9AALDH1A1
SCHEMBL20050846 0.76 LOXL2 (0.40) HTTNPC1RAB9AHDAC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed