Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606131 | 0.81 | TRPV1 (0.43) | TRPV1RPS6KA5GABRA1GABRG2GABRB3 | |
| SCHEMBL19100730 | 0.80 | ALDH1A1 (0.41) | TRPV1RPS6KA5TDO2 | |
| SCHEMBL31346256 | 0.80 | TDO2 (0.35) | GRM5TDO2GRM4DYRK1B | |
| SCHEMBL18298616 | 0.80 | RPS6KA5 (0.38) | TRPV1RPS6KA5EGLN1SORD | |
| SCHEMBL17670232 | 0.80 | RPS6KA5 (0.35) | TRPV1RPS6KA5EGLN1 | |
| SCHEMBL24920862 | 0.76 | MAPT (0.34) | GRM5TDO2GRM4EGLN1 | |
| SCHEMBL22071443 | 0.76 | RPS6KA5 (0.35) | TRPV1RPS6KA5 | |
| SCHEMBL31585397 | 0.76 | GRM5 (0.39) | RPS6KA5GRM5EGLN1 | |
| SCHEMBL19100794 | 0.76 | RPS6KA5 (0.33) | TRPV1RPS6KA5GABRA1GABRG2GABRB3 | |
| SCHEMBL24253886 | 0.75 | GRM5 (0.39) | GRM5TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022314-A1 | TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-02-01 | — | — | WO | disclosed |