SCHEMBL31346256

SCHEMBL31346256

Fc1cnn(-c2ccnc(Br)n2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.35
MBOAT4 Q96T53 1/20 0.33
GRM5 P41594 2/20 0.33
GRM4 Q14833 1/20 0.31
PRKCI P41743 1/20 0.31
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30740344 0.80 TRPV1 (0.39) TDO2GRM5GRM4DYRK1B
SCHEMBL24920862 0.76 MAPT (0.34) TDO2GRM5GRM4
SCHEMBL28431647 0.72 TDO2 (0.37) TDO2MBOAT4GRM5
SCHEMBL30452646 0.72 TDO2 (0.37) TDO2MBOAT4GRM5
SCHEMBL24921233 0.68 CCR1 (0.44) GRM5GRM4
SCHEMBL28396373 0.66 TDO2 (0.40) TDO2GRM4
SCHEMBL31435193 0.66 HCAR2 (0.39) TDO2GRM5
SCHEMBL30539997 0.66 TDO2 (0.37) TDO2GRM5GRM4
SCHEMBL28938115 0.66 TDO2 (0.37) TDO2GRM5
SCHEMBL24921183 0.65 MAP4K1 (0.41) TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522593-B2 Azacycloalkyl carbonyl cyclic amine compound ALIVEXIS, INC. (JP) 2026-01-13 US disclosed
US-20250163041-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND ALIVEXIS, INC. (JP) 2025-05-22 US disclosed
EP-4538264-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND Alivexis, Inc. (JP) 2025-04-16 EP disclosed
CN-119317620-A Azacycloalkyl carbonyl cyclic amine compounds 亚力维克希斯股份有限公司 2025-01-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163041-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND NCF1, ELANE, MPO TDO2 3296/4885MBOAT4 3557/4885GRM5 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.