Water

Water

SCHEMBL30740398

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nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL30740384 0.90 LMNA (0.50) LMNABLM
Water SCHEMBL27077179 0.88 LMNA (0.48) LMNABLM
Water SCHEMBL27077166 0.88 LMNA (0.48) LMNABLM
Water SCHEMBL27077226 0.88 LMNA (0.48) LMNABLM
Water SCHEMBL30740474 0.79
SCHEMBL16469538 0.73
SCHEMBL42290 0.73
SCHEMBL108076 0.73 LMNA (0.71) LMNABLM
Water SCHEMBL4955769 0.70 LMNA (0.67) LMNABLM
SCHEMBL7580335 0.70 LMNA (0.67) LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396581-A Stable AIGS film 纳米系统公司 2024-01-12 CN disclosed