Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740841 | 0.87 | L3MBTL1 (0.38) | HCRTR2HCRTR1NPSR1LMNAL3MBTL1 | |
| SCHEMBL30740738 | 0.85 | PRMT5 (0.38) | HCRTR2HCRTR1NPSR1LMNAL3MBTL1 | |
| SCHEMBL29826374 | 0.85 | GPR119 (0.43) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL30740732 | 0.80 | MRGPRX4 (0.45) | LMNAPRMT5KDM1AMRGPRX4CHEK2 | |
| SCHEMBL30740781 | 0.78 | KDM1A (0.44) | HCRTR2NPSR1LMNAKMT2APRMT5 | |
| SCHEMBL29826235 | 0.71 | GPR119 (0.45) | LMNAKMT2AKDM4E | |
| SCHEMBL29826499 | 0.70 | GPR119 (0.46) | LMNAKMT2AKDM4E | |
| SCHEMBL25155946 | 0.69 | ALOX5AP (0.43) | NPSR1LMNAKMT2APRMT5MEN1 | |
| SCHEMBL31359908 | 0.69 | ALOX5AP (0.43) | NPSR1LMNAKMT2APRMT5MEN1 | |
| SCHEMBL31360101 | 0.69 | ALOX5AP (0.43) | NPSR1LMNAKMT2APRMT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |