Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740841 | 0.87 | L3MBTL1 (0.38) | PRMT5L3MBTL1NPSR1MAPTLMNA | |
| SCHEMBL30740694 | 0.85 | HCRTR2 (0.41) | PRMT5L3MBTL1NPSR1MAPTLMNA | |
| SCHEMBL29826499 | 0.85 | GPR119 (0.46) | LMNAGPR119 | |
| SCHEMBL30740732 | 0.80 | MRGPRX4 (0.45) | PRMT5LMNAALOX5APFEN1CHEK2 | |
| SCHEMBL30740781 | 0.78 | KDM1A (0.44) | PRMT5NPSR1MAPTLMNAALOX5AP | |
| SCHEMBL29826235 | 0.71 | GPR119 (0.45) | LMNAGPR119 | |
| SCHEMBL29826374 | 0.70 | GPR119 (0.43) | MAPTLMNAGPR119 | |
| SCHEMBL26802554 | 0.69 | GPR119 (0.47) | F2RL3ALOX5APFEN1GPR119 | |
| SCHEMBL26802291 | 0.69 | GPR119 (0.47) | F2RL3ALOX5APFEN1GPR119 | |
| SCHEMBL2512853 | 0.69 | METTL3 (0.45) | PRMT5L3MBTL1NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |