Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826502 | 0.85 | MRGPRX4 (0.48) | MRGPRX4LMNAPDE4BGPR119 | |
| SCHEMBL30740841 | 0.81 | L3MBTL1 (0.38) | PDE8BLMNAKDM1APRMT5GPR119 | |
| SCHEMBL30740694 | 0.80 | HCRTR2 (0.41) | MRGPRX4LMNAKDM1APRMT5CHEK2 | |
| SCHEMBL30740738 | 0.80 | PRMT5 (0.38) | PDE8BLMNAKDM1APRMT5GPR119 | |
| SCHEMBL30740781 | 0.78 | KDM1A (0.44) | PDE8BALDH1A1LMNATSHRKDM1A | |
| SCHEMBL30740730 | 0.76 | MRGPRX4 (0.46) | MRGPRX4ALDH1A1LMNATSHREPHA2 | |
| SCHEMBL30745366 | 0.75 | MRGPRX4 (0.49) | MRGPRX4ALDH1A1LMNATSHREPHA2 | |
| SCHEMBL30740715 | 0.74 | KMT2A (0.52) | MRGPRX4ALDH1A1LMNATSHRAHCY | |
| SCHEMBL30745354 | 0.73 | ALDH1A1 (0.44) | PDE8BALDH1A1LMNATSHREPHA2 | |
| SCHEMBL24793341 | 0.73 | MRGPRX4 (0.48) | MRGPRX4ALDH1A1PDE4BPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |