Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SORD | Q00796 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740770 | 0.87 | GPR119 (0.37) | HSD11B1GPR119POLBKDM4E | |
| SCHEMBL30740793 | 0.84 | NPC1 (0.41) | HSD11B1GPR119POLBKDM4ENPC1 | |
| SCHEMBL29826104 | 0.82 | GPR119 (0.52) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30740739 | 0.79 | GPR119 (0.40) | GPR119 | |
| SCHEMBL30740761 | 0.78 | MEN1 (0.39) | HSD11B1GPR119POLBKDM4EALDH1A1 | |
| SCHEMBL30740772 | 0.78 | GPR119 (0.38) | GPR119POLB | |
| SCHEMBL30740852 | 0.75 | HSD11B1 (0.41) | HSD11B1GPR119POLBKDM4EALDH1A1 | |
| SCHEMBL30668743 | 0.74 | GPR119 (0.44) | HSD11B1GPR119NPC1 | |
| SCHEMBL30731233 | 0.73 | GPR119 (0.51) | HSD11B1GPR119KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29223963 | 0.72 | GPR119 (0.48) | HSD11B1GPR119KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |